PropertyValue
?:abstract
  • The SARS-CoV-2 virus causes a respiratory distress syndrome, the main symptom of COVID-19 (for \'COronaVIrus Disease 2019\'). This infectious disease has been causing a major health and socio-economic pandemic since December 2019. The pulmonary alveolus is regarded as the main target of SARS-CoV-2. However, this coronavirus is capable of directly or indirectly affecting other organs, including the kidneys. Here, we summarize the presumed pathophysiology of COVID-19 renal disease. The incidence of acute kidney injury ranges from 0,5 to 22 % of all patients infected with SARS-CoV-2. The need for renal replacement therapy is reported in 5-9 % of patients in intensive care. Histological analysis of renal biopsies mainly shows acute tubular necrosis of varying severity, as well as the congestion of glomerular and peri-tubular capillaries. Endothelitis has been described in few cases. Evidence for a factual inflammation of the glomerulus remains controversial. The medium/long term consequences of COVID-19 nephropathy are unknown and will deserve a tight follow-up.
is ?:annotates of
?:creator
?:externalLink
?:journal
  • Revue_medicale_de_Liege
?:license
  • unk
?:pmid
?:pmid
  • 33211431.0
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • Medline
?:title
  • [Kidney injury in COVID-19].
?:type
?:year
  • 2020

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