PropertyValue
?:abstract
  • The COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2 has spread globally, with >52,000 cases in California as of May 4, 2020. Here we investigate the genomic epidemiology of SARS-CoV-2 in Northern California from late January to mid-March 2020, using samples from 36 patients spanning 9 counties and the Grand Princess cruise ship. Phylogenetic analyses revealed the cryptic introduction of at least 7 different SARS-CoV-2 lineages into California, including epidemic WA1 strains associated with Washington State, with lack of a predominant lineage and limited transmission between communities. Lineages associated with outbreak clusters in 2 counties were defined by a single base substitution in the viral genome. These findings support contact tracing, social distancing, and travel restrictions to contain SARS-CoV-2 spread in California and other states.
?:creator
?:doi
?:doi
  • 10.1126/science.abb9263
?:journal
  • Science
?:license
  • cc-by
?:pdf_json_files
  • document_parses/pdf_json/f5ff50868a40362ba3d87df998f5eee8b9b89e8c.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7286545.xml.json
?:pmcid
?:pmid
?:pmid
  • 32513865.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California
?:type
?:year
  • 2020-06-08

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