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?:abstract
  • In the preceding months, the novel SARS-CoV-2 pandemic has devastated global communities The need for safe and effective prophylactic and therapeutic treatments to combat COVID-19 - the human disease resulting from SARS-CoV-2 infection - is clear Here, we present recent developments in the effort to combat COVID-19 and consider whether SARS-CoV-2 may potentially interact with the host autophagy pathway Abbreviations: ACE2, angiotensin converting enzyme II;βCoV, betacoronavirus;COVID-19, Coronavirus Disease 2019;CQ, chloroquine;DMV, double-membrane vesicle;GI, gastrointestinal;HCQ, hydroxychloroquine;IL, interleukin;MAP1LC3/LC3, microtubule associated protein 1 light chain 3;MEFs, mouse embryonic fibroblasts;MERS-CoV, Middle East respiratory syndrome coronavirus;MHV, murine hepatitis virus;PE, phosphatidylethanolamine;SARS-CoV, severe acute respiratory syndrome coronavirus;SARS-CoV-2, severe acute respiratory syndrome coronavirus 2;TMPRSS2, transmembrane serine protease 2;TNF, tumor necrosis factor;WHO, World Health Organization
is ?:annotates of
?:creator
?:journal
  • Autophagy
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?
?:type
?:who_covidence_id
  • #913052
?:year
  • 2020

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