PropertyValue
?:abstract
  • OBJECTIVES: To assess disease trends, testing practices, community surveillance, case-fatality and excess deaths in children as compared with adults during the first pandemic peak in England. SETTING: England. PARTICIPANTS: Children with COVID-19 between January and May 2020. MAIN OUTCOME MEASURES: Trends in confirmed COVID-19 cases, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positivity rates in children compared with adults; community prevalence of SARS-CoV-2 in children with acute respiratory infection (ARI) compared with adults, case-fatality rate in children with confirmed COVID-19 and excess childhood deaths compared with the previous 5 years. RESULTS: Children represented 1.1% (1,408/129,704) of SAR-CoV-2 positive cases between 16January 2020 and 3 May 2020. Intotal, 540 305 people were tested forSARS-COV-2 and 129,704(24.0%) were positive. In children aged <16 years, 35,200 tests wereperformed and 1408 (4.0%) were positive forSARS-CoV-2, 19.1%–34.9% adults.Childhood cases increased from mid-March and peaked on 11 April beforedeclining. Among 2,961individuals presenting with ARI in primary care, 351 were children and 10 (2.8%) were positive compared with 9.3%–45.5% in adults. Eightchildren died and four (case-fatality rate, 0.3%;95% CI0.07% to 0.7%) were due to COVID-19.We found no evidence of excess mortality in children. CONCLUSIONS: Children accounted for a very small proportion of confirmed cases despite the large numbers of children tested. SARS-CoV-2 positivity was low even in children with ARI. Our findings provide further evidence against the role of children in infection and transmission of SARS-CoV-2.
?:creator
?:doi
  • 10.1136/archdischild-2020-320042
?:doi
?:journal
  • Arch_Dis_Child
?:license
  • cc-by-nc
?:pdf_json_files
  • document_parses/pdf_json/259bfd978c1e82fbd1296e0a63ee442aa9dca70c.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7431771.xml.json
?:pmcid
?:pmid
?:pmid
  • 32796006.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • COVID-19 in children: analysis of the first pandemic peak in England
?:type
?:year
  • 2020-08-05

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