gxf2fnt1

Property	Value
?:abstract	SIMPLE SUMMARY: Infectious bronchitis (IB) is one of the more prevalent diseases in poultry, and it is caused by a virus belonging to the Coronaviridae family, the infectious bronchitis virus (IBV), a Gammacoronavirus which is related to the Betacoronavirus SARSCov-2 causing COVID-19 in humans. IB is mainly controlled by biosecurity and vaccines, although, it is a very challenging issue because the viral populations are constantly evolving by several factors. One of these factors is the same vaccines used for IB control, this could explain by recombination, reversion to virulence, or by favoring virus serotype selection. Thus, a human role in the change of viral populations can be identified by the IBV vaccine usage, this must be considered to achieve effective IB control. ABSTRACT: Infectious bronchitis virus (IBV) remains one of the most important diseases impacting poultry today. Its high adaptive capacity, attributable to the high mutation rate associated with its ssRNA(+), is one of its more important features. While biosecurity procedures and barriers have been shown to be preponderant factors in minimizing the impact of infectious bronchitis (IB), the environment and procedures associated with intensive poultry systems greatly influence the viral population dynamics. High-density poultry flocks facilitate recombination between different viruses, and even with live attenuated vaccines, which can change the dominant circulating field strains. Furthermore, the remaining issue of reversion to virulence gives rise to significant problems when vaccinal strains are introduced in places where their pathogenic variants have not been reported. Under specific conditions, live attenuated vaccines could also change the frequency of circulating viruses and enable replacement between different field strains. In summary, under a comprehensive approach, while vaccination is one of the most essential tools for controlling IB, the veterinarians, farmers, and official services role in its usage is central to minimizing alteration in a malleable viral population. Otherwise, vaccination is ultimately counterproductive.
is ?:annotates of	<https://research.tib.eu/covid-19/entity/gxf2fnt1_hasAnnotation_C0004419> <https://research.tib.eu/covid-19/entity/gxf2fnt1_hasAnnotation_C0042776> <https://research.tib.eu/covid-19/entity/gxf2fnt1_hasAnnotation_C1825598> <https://research.tib.eu/covid-19/entity/gxf2fnt1_hasAnnotation_C3272452> <https://research.tib.eu/covid-19/entity/gxf2fnt1_hasAnnotation_C3816499> <https://research.tib.eu/covid-19/entity/gxf2fnt1_hasAnnotation_C4321252>
?:creator	<https://research.tib.eu/covid-19/entity/Guzm%C3%A1n%2C_Miguel%3B_Hidalgo%2C_H%C3%A9ctor>
?:doi	10.3390/ani10112058
?:doi	<https://research.tib.eu/covid-19/entity/10.3390/ani10112058>
?:journal	Animals_(Basel)
?:license	cc-by
?:pdf_json_files	document_parses/pdf_json/2fa67179d77768afea5b5f17dc7e4d1ac5ce4285.json
?:pmc_json_files	document_parses/pmc_json/PMC7694962.xml.json
?:pmcid	<https://research.tib.eu/covid-19/entity/PMC7694962>
?:pmid	<https://research.tib.eu/covid-19/entity/33171704.0>
?:pmid	33171704.0
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
?:sha_id	<https://research.tib.eu/covid-19/entity/2fa67179d77768afea5b5f17dc7e4d1ac5ce4285>
?:source	Medline; PMC
?:title	Live Attenuated Infectious Bronchitis Virus Vaccines in Poultry: Modifying Local Viral Populations Dynamics
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:year	2020-11-07

Property

Value

?:abstract

SIMPLE SUMMARY: Infectious bronchitis (IB) is one of the more prevalent diseases in poultry, and it is caused by a virus belonging to the Coronaviridae family, the infectious bronchitis virus (IBV), a Gammacoronavirus which is related to the Betacoronavirus SARSCov-2 causing COVID-19 in humans. IB is mainly controlled by biosecurity and vaccines, although, it is a very challenging issue because the viral populations are constantly evolving by several factors. One of these factors is the same vaccines used for IB control, this could explain by recombination, reversion to virulence, or by favoring virus serotype selection. Thus, a human role in the change of viral populations can be identified by the IBV vaccine usage, this must be considered to achieve effective IB control. ABSTRACT: Infectious bronchitis virus (IBV) remains one of the most important diseases impacting poultry today. Its high adaptive capacity, attributable to the high mutation rate associated with its ssRNA(+), is one of its more important features. While biosecurity procedures and barriers have been shown to be preponderant factors in minimizing the impact of infectious bronchitis (IB), the environment and procedures associated with intensive poultry systems greatly influence the viral population dynamics. High-density poultry flocks facilitate recombination between different viruses, and even with live attenuated vaccines, which can change the dominant circulating field strains. Furthermore, the remaining issue of reversion to virulence gives rise to significant problems when vaccinal strains are introduced in places where their pathogenic variants have not been reported. Under specific conditions, live attenuated vaccines could also change the frequency of circulating viruses and enable replacement between different field strains. In summary, under a comprehensive approach, while vaccination is one of the most essential tools for controlling IB, the veterinarians, farmers, and official services role in its usage is central to minimizing alteration in a malleable viral population. Otherwise, vaccination is ultimately counterproductive.

is ?:annotates of