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In absence of any specific medication or vaccine till now, experimentation has reached new heights With lockdown imposed in almost every country and huge economic losses the search for a suitable vaccine has still been unsuccessful In this study we have approached through in-silico method or reverse vaccinology taking advantage of the genome sequence of the novel coronavirus We created a multi-epitope model vaccine which can elicit both humoral as well as cell-mediated immune response It is also docked with toll-like receptor 8 TLR-8 The sequence obtained is antigenic, non-allergenic and 86 3% residues are in favourable region of Ramachandran plot This sequence might have good hope of emerging as the vaccine of the current pandemic if studied more in depth
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Application of In-Silico Reverse Vaccinology for Designing Multi-Epitope Vaccine Against Coronavirus
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