PropertyValue
?:abstract
  • The emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing global health crises. Children can be infected, but are less likely to develop severe neurological abnormalities compared with adults. However, whether SARS-CoV-2 can directly cause neurological impairments in pediatric patients is not known. The possible evolutionary and molecular relationship between SARS-CoV-2 and non-segmented RNA viruses were examined with reference to neurological disorders in pediatric patients. SARS-CoV-2 shares similar functional domains with neuroinvasive and neurotropic RNA viruses. The Spike 1 (S1) receptor binding domain and the cleavage sites at S1/S2 boundary are less conserved compared with the S2 among coronaviruses.
?:creator
?:doi
?:doi
  • 10.1007/s13365-020-00913-5
?:journal
  • J_Neurovirol
?:license
  • no-cc
?:pdf_json_files
  • document_parses/pdf_json/434688a7247233278229c7daeec430378ea0e260.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7556565.xml.json
?:pmcid
?:pmid
?:pmid
  • 33057966.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Potential neuroinvasive and neurotrophic properties of SARS-CoV-2 in pediatric patients: comparison of SARS-CoV-2 with non-segmented RNA viruses
?:type
?:year
  • 2020-10-14

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