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?:abstract
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El nuevo coronavirus 2019, posteriormente conocido como SARS-CoV-2 ha generado una nueva pandemia y hoy se reúnen esfuerzos para su control Se hacen investigaciones de la estructura genómica del virus y de sus mecanismos patogénicos, primero describiendo su estructura para así comprender su función, también en relación a su unión con los receptores que se expresan en los órganos más afectados La relación estructural que se encuentra en los Dominios de Unión de SARS-CoV-2, son compatibles con los dominios de unión de SARS-CoV Hay diferencias en algunos segmentos de la cadena, pero esto no parece alterar la letalidad del virus El uso de técnicas de criomicroscopía hizo posible reconocer estructuras de la superficie viral y hacer una descripción de su unión al receptor ECA2 Además de esta manera se puede fijar objetivos con potencial terapéutico The new coronavirus 2019, later known as SARS-CoV-2, has generated a new pandemic and today efforts are being made to control it, investigations are made of the genomic structure of the virus and also of pathogenic mechanisms, first describing its structure and thus its function, as well as in relation to its union with the receptors that are expressed in its most affected organs The structural relationship found in the SARS-CoV-2 Binding Domains are compatible with the SARS-CoV binding domains There are differences in some segments of the chain, but this does not seem to alter the lethality of the virus The use of cryomicroscopy techniques helped to recognize viral surface structures and to describe their binding to the ECA2 receptor In addition, in this way, targets with therapeutic potential can be set
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The new coronavirus 2019, later known as SARS-CoV-2, has generated a new pandemic and today efforts are being made to control it, investigations are made of the genomic structure of the virus and also of pathogenic mechanisms, first describing its structure and thus its function, as well as in relation to its union with the receptors that are expressed in its most affected organs The structural relationship found in the SARS-CoV-2 Binding Domains are compatible with the SARS-CoV binding domains There are differences in some segments of the chain, but this does not seem to alter the lethality of the virus The use of cryomicroscopy techniques helped to recognize viral surface structures and to describe their binding to the ECA2 receptor In addition, in this way, targets with therapeutic potential can be set
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