PropertyValue
?:abstract
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can trigger a cytokine storm in the pulmonary tissue by releasing various types of mediators, leading to acute respiratory distress syndrome (ARDS). Increased neutrophil-to-lymphocyte ratio as well as CD4+ T lymphopenia is reported in cases with novel coronavirus disease (COVID-19), meanwhile lymphopenia is a significant finding in the majority of COVID-19 cases with severe phenotype. Moreover, excessive activation of monocyte/macrophage and cytokine storms is associated with the severity of the disease and the related complications in SARS-CoV-2 infection. Understanding the immune response dysregulation in COVID-19 is essential to develop more effective diagnostic, therapeutic, and prophylactic strategies in this pandemic. This article is protected by copyright. All rights reserved.
is ?:annotates of
?:creator
?:journal
  • Cell_biol._int
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Dysregulation of the Immune Response in COVID-19
?:type
?:who_covidence_id
  • #954080
?:year
  • 2020

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