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Happy hypoxemia is a clinical condition that is baffling the physicians world over during this COVID 19 pandemic, which manifests with little or no dyspnoea in the presence of severe hypoxemia Many mechanisms have been put forth to explain this paradoxical phenomenon This article revisits some of the basic physiological concepts in respiratory physiology Carbon dioxide is the primary controller of chemical regulation of respiration, not the oxygen as the body has mechanisms to withstand wide fluctuations in blood oxygen level Hypercapnia is a late manifestation when compared to hypoxia in conditions where diffusion of respiratory gases is impaired, like in acute respiratory distress syndrome that often complicates severe COVID 19 cases New findings suggest an additional role of carbon dioxide in the pathogenesis of dyspnoea, through its contribution to the development of pulmonary edema [ABSTRACT FROM AUTHOR] Copyright of International Archives of Integrated Medicine is the property of International Archives of Integrated Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder\'s express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )
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International_Archives_of_Integrated_Medicine
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Happy hypoxemia: What has been forgotten
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