PropertyValue
?:abstract
  • Based on the announcement of the World Health Organization (WHO) in 2018, the Wuhan pneumonia caused by an unknown etiology should be recognized as the first Disease X Later, the pathogen was identified to be a novel coronavirus denoted 2019-nCoV, which has 79 5% and 96% whole genome sequence identify to SARS-CoV and bat SARS-related coronavirus (SARSr-CoV-RaTG13), respectively, suggesting its potential bat origin With high human-to-human transmission rate (R0), 2019-nCoV has quickly spread in China and other countries, resulting in 34,953 confirmed cases and 725 deaths as of 8 February 2020, thus calling for urgent development of therapeutics and prophylactics Here we suggest renaming 2019-nCoV as \'transmissible acute respiratory syndrome coronavirus (TARS-CoV)\' and briefly review the advancement of research and development of neutralizing antibodies and vaccines targeting the receptor-binding domain (RBD) and viral fusion inhibitors targeting the heptad repeat 1 (HR1) domain in spike protein of 2019-nCoV
is ?:annotates of
?:creator
?:journal
  • Virologica_Sinica
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • The first Disease X is caused by a highly transmissible acute respiratory syndrome coronavirus. (Special Issue: SARS-CoV-2 and COVID-19.)
?:type
?:who_covidence_id
  • #959348
?:year
  • 2020

Metadata

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