| Property | Value |
|---|
|
?:abstract
|
-
Coronavirus disease 2019 (COVID-19) pandemic gripped the globe SARS-CoV-2 is highly infectious and is susceptible to all populations Immunosuppressed patients have greater risk for opportunistic infections However, the understanding regarding the biological characteristics of SARSCoV-2 in immunosuppressed patients remains unclear Herein, we present a case of prolonged shedding of SARS-CoV-2 in a liver transplant patient with COVID-19 A 61-year-old male post liver transplant was confirmed COVID-19 infection on day 10 of illness onset The patient has received immunosuppressive treatment for over 11 years and has a history of hypertension for 10 years With antiviral treatment and temporary discontinuation of tacrolimus immunosuppression, he had complete clinical symptoms relieve on day 24 However, recurrently positive tests of SARS-CoV-2 RNA were presented on day 35 and on day 39 after two consecutive negative tests IgG antibody test for SARS-CoV-2 was positive with IgM negative on day 41 The final shedding duration lasted 52 days Prolonged shedding of SARS-CoV-2 should be a matter of concern and might attribute to long-term immunosuppression Therefore, dynamic surveillance and prolonged quarantine are required for immunocompromised individuals Further data should be collected to investigate if there is a universal prolonged shedding window of SARS-CoV-2 in immunosuppressed patients
|
|
is
?:annotates
of
|
|
|
?:creator
|
|
|
?:journal
|
|
|
?:license
|
|
|
?:publication_isRelatedTo_Disease
|
|
|
is
?:relation_isRelatedTo_publication
of
|
|
|
?:source
|
|
|
?:title
|
-
Prolonged shedding of SARS-CoV-2 in an elderly liver transplant patient infected by COVID-19: a case report
|
|
?:type
|
|
|
?:who_covidence_id
|
|
|
?:year
|
|
![[This page as RDF]](https://research.tib.eu/covid-19/static/rdf-icon.gif){kind=icon}