hrzuezfq

Property	Value
?:abstract	ABSTRACT: Background: The interval between inpatient hospitalization for symptomatic coronary artery disease (CAD) and post-discharge office consultation is a vulnerable period for adverse events. Tools to help guide patients during this susceptible time are needed. Methods: To determine whether a smartphone application (app) deployed following percutaneous coronary intervention (PCI) can safely improve the transition to ambulatory care, we customized content on a digital health platform for hospitalized patients receiving PCI which included education, tracking, reminders and live health coaches. We conducted a single-arm open-label pilot study of the app at two academic medical centers in a single health system, with subjects enrolled 02/2018-05/2019 and 1:3 propensity-matched historical controls from 01/2015-12/2017. To evaluate feasibility and efficacy, we assessed 30-day hospital readmission (primary), outpatient cardiovascular follow-up, and cardiac rehabilitation (CR) enrollment as recorded in the health system. Outcomes were assessed by Cox Proportional Hazards model. Results: 1676 patients were excluded due to pre-specified criteria including medical complexity, language barrier, and elderly age. 118 of 324 eligible (36.4%) 21-85 year-old patients who underwent PCI for either symptomatic CAD or acute coronary syndrome and who owned a smartphone or tablet enrolled. Mean age was 62.5 (9.7) years, 87 (73.7%) were male, 40 of 118 (33.9%) had type 2 diabetes mellitus, 68 (57.6%) enrolled underwent PCI for MI and 59 (50.0%) had previously known CAD; demographics were similar among matched historical controls. No significant difference existed in all-cause readmission within 30 days (8.5% app vs 9.6% control, p=0.699) or 90 days (16.1% app vs 19.5% control, p=0.394). Rates of both 90-day CR enrollment (HR 1.99, 95% CI 1.30-3.06) and 1-month cardiovascular follow up (HR 1.83, 95% CI 1.43-2.34) were increased. Weekly engagement at 30- and 90-days, as measured by percentage of weeks with at least one day of completion of tasks, was mean (SD) 73.5% (33.9%) and 63.5% (40.3%). Spearman correlation analyses indicated similar engagement across age, sex, and cardiovascular risk factors. Conclusions: A post-PCI smartphone app with live health coaches yielded similarly high engagement across demographics and safely increased attendance in cardiac rehabilitation. Larger prospective randomized controlled trials are necessary to test whether this app improves cardiovascular outcomes following PCI.
is ?:annotates of	<https://research.tib.eu/covid-19/entity/hrzuezfq_hasAnnotation_C0877248> <https://research.tib.eu/covid-19/entity/hrzuezfq_hasAnnotation_C1417646>
?:creator	<https://research.tib.eu/covid-19/entity/Paruchuri%2C_K.%3B_Finneran%2C_P.%3B_Marston%2C_N._A.%3B_Healy%2C_E._W.%3B_Andreo%2C_J.%3B_Lynch%2C_R.%3B_Blood%2C_A._J.%3B_Jones-O%27Connor%2C_M.%3B_Lander%2C_B.%3B_Kelly%2C_N.%3B_Vivaldi%2C_M._T.%3B_Traynor%2C_K.%3B_Wiviott%2C_S.%3B_Natarajan%2C_P.>
?:doi	<https://research.tib.eu/covid-19/entity/10.1101/2020.11.08.20217653>
?:doi	10.1101/2020.11.08.20217653
?:externalLink	<http://medrxiv.org/cgi/content/short/2020.11.08.20217653v1%3Frss%3D1>
?:license	medrxiv
?:pdf_json_files	document_parses/pdf_json/be817de435859febdc256bcb0571750ed20faa5b.json
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
?:sha_id	<https://research.tib.eu/covid-19/entity/be817de435859febdc256bcb0571750ed20faa5b>
?:source	MedRxiv
?:title	OUTCOMES OF A SMARTPHONE-BASED APPLICATION WITH LIVE HEALTH-COACHING POST-PERCUTANEOUS CORONARY INTERVENTION
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:year	2020-11-12

Property

Value

?:abstract

ABSTRACT: Background: The interval between inpatient hospitalization for symptomatic coronary artery disease (CAD) and post-discharge office consultation is a vulnerable period for adverse events. Tools to help guide patients during this susceptible time are needed. Methods: To determine whether a smartphone application (app) deployed following percutaneous coronary intervention (PCI) can safely improve the transition to ambulatory care, we customized content on a digital health platform for hospitalized patients receiving PCI which included education, tracking, reminders and live health coaches. We conducted a single-arm open-label pilot study of the app at two academic medical centers in a single health system, with subjects enrolled 02/2018-05/2019 and 1:3 propensity-matched historical controls from 01/2015-12/2017. To evaluate feasibility and efficacy, we assessed 30-day hospital readmission (primary), outpatient cardiovascular follow-up, and cardiac rehabilitation (CR) enrollment as recorded in the health system. Outcomes were assessed by Cox Proportional Hazards model. Results: 1676 patients were excluded due to pre-specified criteria including medical complexity, language barrier, and elderly age. 118 of 324 eligible (36.4%) 21-85 year-old patients who underwent PCI for either symptomatic CAD or acute coronary syndrome and who owned a smartphone or tablet enrolled. Mean age was 62.5 (9.7) years, 87 (73.7%) were male, 40 of 118 (33.9%) had type 2 diabetes mellitus, 68 (57.6%) enrolled underwent PCI for MI and 59 (50.0%) had previously known CAD; demographics were similar among matched historical controls. No significant difference existed in all-cause readmission within 30 days (8.5% app vs 9.6% control, p=0.699) or 90 days (16.1% app vs 19.5% control, p=0.394). Rates of both 90-day CR enrollment (HR 1.99, 95% CI 1.30-3.06) and 1-month cardiovascular follow up (HR 1.83, 95% CI 1.43-2.34) were increased. Weekly engagement at 30- and 90-days, as measured by percentage of weeks with at least one day of completion of tasks, was mean (SD) 73.5% (33.9%) and 63.5% (40.3%). Spearman correlation analyses indicated similar engagement across age, sex, and cardiovascular risk factors. Conclusions: A post-PCI smartphone app with live health coaches yielded similarly high engagement across demographics and safely increased attendance in cardiac rehabilitation. Larger prospective randomized controlled trials are necessary to test whether this app improves cardiovascular outcomes following PCI.

is ?:annotates of