| Property | Value |
|---|
|
?:abstract
|
-
BACKGROUND Low-dose computed tomography (LDCT) screening reduces lung cancer mortality by at least 20%. The COVID-19 pandemic required an unprecedented shutdown in our institutional LDCT program. The purpose of this study was to examine the impact of COVID-19 on lung cancer screening and subsequent cancer diagnosis. STUDY DESIGN We analyzed our prospective institutional LDCT screening database, which began in 2012; 2,153 patients have participated. Monthly average LDCT were compared between baseline (January 2017-February 2020) and COVID-19 periods (March 2020-July 2020). RESULTS LDCT was suspended on March 13, 2020 and 818 screening visits were cancelled. Phased reopening began on May 5th and full opening on June 1st. Total monthly LDCT (146±31 vs. 39±40, p<0.01) and new patient monthly LDCT (56±14 vs. 15±17, p<0.01) were significantly decreased during COVID-19 period. New patient monthly LDCT has remained low despite resuming full operations. Three and 6-month interval follow up LDCTs were prioritized and were significantly increased compared to baseline (11±4 vs. 30±4, p<0.01). The \'no-show\' rate was significantly increased from baseline (15% vs 40%, p<0.04). Most concerning, the percentage of patients with lung nodules suspicious for malignancy (Lung RADS 4) were significantly increased after operations resumed (8% vs. 29%, p<0.01). CONCLUSION COVID-19 caused significant disruption in lung cancer screening, leading to a decrease in new patients screened and an increased proportion of nodules suspicious for malignancy once screening resumed. Using lung cancer and the LDCT screening program as a model, this early analysis shows the unrecognized consequences related to the pandemic for screening programs and cancer care.
|
|
is
?:annotates
of
|
|
|
?:creator
|
|
|
?:doi
|
-
10.1016/j.jamcollsurg.2020.12.002
|
|
?:doi
|
|
|
?:journal
|
-
Journal_of_the_American_College_of_Surgeons
|
|
?:license
|
|
|
?:pmid
|
|
|
?:pmid
|
|
|
?:publication_isRelatedTo_Disease
|
|
|
?:source
|
|
|
?:title
|
-
Impact of the COVID-19 Pandemic on Lung Cancer Screening Program and Subsequent Lung Cancer.
|
|
?:type
|
|
|
?:year
|
|
![[This page as RDF]](https://research.tib.eu/covid-19/static/rdf-icon.gif){kind=icon}