?:abstract
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In December 2019, the novel coronavirus pneumonia broke out in Wuhan, Hubei, and then spread across China and the world, which posed a threat to public health and safety.The symptoms caused by the novel coronavirus (SARS-CoV-2) mainly involve the respiratory system, but no literature has been reported whether it can induce pathological changes in the male reproductive system. According to the fact that SARS-CoV-2 can infect the cells expressing angiotensin-converting enzyme 2 (ACE2), which can be distributed in the corpus cavernosum, testis and other male reproductive organs and may also participate in erectile function, spermatogenesis, sperm motility and androgen metabolism through the ACE2-Ang-(1-7)-Mas axis in the renin-angiotensin system(RAS), it can be deduced that SARS-CoV-2 may affect these physiological processes of male reproduction.
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