PropertyValue
?:abstract
  • Down syndrome (DS) predisposes to severe immunologic reaction secondary to infectious triggers. Here we report a paediatric DS patient with COVID-19 who developed a hyperinflammatory syndrome, severe ARDS and secondary HLH requiring PICU admission and treatment with steroids, IVIG and Remdesivir. Investigations into genetic susceptibilities for COVID-19 and SARS-CoV-2-associated complications warrants systematic clinical and scientific studies.
is ?:annotates of
?:creator
?:doi
?:doi
  • 10.1093/jpids/piaa148
?:journal
  • J_Pediatric_Infect_Dis_Soc
?:license
  • no-cc
?:pdf_json_files
  • document_parses/pdf_json/7a4520cfc38c5d0430c1d19ade95fd14e90e4006.json
?:pmcid
?:pmid
?:pmid
  • 33188394.0
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:sha_id
?:source
  • Medline; PMC
?:title
  • SARS-CoV-2 triggering severe ARDS and secondary HLH in a 3-year-old child with Down syndrome
?:type
?:year
  • 2020-11-14

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