PropertyValue
?:abstract
  • Due to the reported high ability of virulence of COVID_19 in recent months, several studies have been conducted to discover and introduce COVID_19 antiviral drugs The results of numerous studies have shown that protease inhibitors , which make uthe major part of plant derivatives can therefore be very effective in controlling virus-induced infection The aim of this research is the bioinformatical study of COVID_19 inhibition by Secendary Metabolite of medicinal herbs This is a descriptive-analytic study In the present study , the structure of Secendary Metabolite and COVID_19 protease was received from the databases such as PubChem and Protein Data Bank (PDB) After that, Molecular Docking was performed by MVD(molegro virtual docker) software The results are identified to have inhibitory activities against novel COVID-19 protease Of these compounds, Curcumin has a stronger bond and high affinity with protease Finally, with due attention to the high effectiveness function of plant compounds, we can conclude that these compounds may be considered as effectire COVID_19 antiprotease drugs
is ?:annotates of
?:creator
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Inhibitory Effect of Eight Secondary Metabolites from Conventional Medicinal Plants on COVID_19 Virus Protease by Molecular Docking Analysis
?:type
?:who_covidence_id
  • #269
?:year
  • 2020

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