PropertyValue
?:abstract
  • Vitamin C, also known as L-ascorbic acid, is an essential vitamin with pleiotropic functions, ranging from antioxidant to anti-microbial functions. Evidence suggests that vitamin C acts against inflammation, oxidative stress, autophagy chaos, and immune dysfunction. The ability to activate and enhance the immune system makes this versatile vitamin a prospective therapeutic agent amid the current situation of coronavirus disease 2019 (COVID-19). Being highly effective against the influenza virus, causing the common cold, vitamin C may also function against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its associated complications. Severe infections need higher doses of the vitamin to compensate for the augmented inflammatory response and metabolic demand that commonly occur during COVID-19. Compelling evidence also suggests that a high dose of vitamin C (1.5 g/kg body weight) in inflammatory conditions can result in effective clinical outcomes and thus can be employed to combat COVID-19. However, further studies are crucial to delineate the mechanism underlying the action of vitamin C against COVID-19. The current review aims to reposition vitamin C as an alternative approach for alleviating COVID-19-associated complications.
is ?:annotates of
?:creator
?:doi
  • 10.3947/ic.2020.52.4.461
?:doi
?:externalLink
?:journal
  • Infect_Chemother
?:license
  • cc-by-nc
?:pdf_json_files
  • document_parses/pdf_json/44955e520128f60bfddd7355f4e6f5e31e7575ab.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7779993.xml.json
?:pmcid
?:pmid
?:pmid
  • 33263242.0
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:sha_id
?:source
  • Medline; PMC
?:title
  • Repositioning Vitamin C as a Promising Option to Alleviate Complications associated with COVID-19
?:type
?:year
  • 2020-11-24

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