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?:abstract
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OBJECTIVE: To retrospectively analyze the symptoms and characteristics of nervous system damage in severe/critically severe patients with coronavirus disease 2019 (COVID-19) in Sichuan province, with a view to providing basic references for the prevention and treatment of COVID-19 METHODS: A total of 90 patients with severe/critically severe COVID-19 were included, who were diagnosed and treated in COVID-19 designated hospital of Sichuan province from 11 January 2020 to 20 March 2020 Clinical features, test results, treatment options and clinical outcomes were analyzed retrospectively RESULTS: Of 90 patients, there were 54 males and 36 females, with an average age of (53 90±16 92) years In addition to the classic symptoms such as fever and/or respiratory symptoms, 53 patients also had various degrees of neurologic manifestations, including 33 cases of fatigue, 21 muscle soreness, 12 dizziness, 8 headaches, 3 mental disorders, and 1 consciousness disorders and 1 case of neck pain Compared with the patients without neurologic manifestations, those with neurologic manifestations took a longer time from admission to diagnosis of COVID-19 ( P<0 05), and received more antifungal treatment ( P<0 05) CONCLUSIONS: Neurological symptoms are not uncommon in severe/critically severe patients with COVID-19, and it\'s relatively difficult in the treatment It should be paid attention in order to avoid misdiagnosis
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