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Understanding which children are at increased risk for poor outcome with COVID-19 is critical. In this study, we link pediatric population–based data from the US Center for Disease Control and Prevention to COVID-19 hospitalization and in-hospital death. In 27,045 US children with confirmed COVID-19, we demonstrate that African American [OR 2.28 (95% CI: 1.93, 2.70)] or mixed race [OR 2.95 (95% CI: 2.28, 3.82)] and an underlying medical condition [OR 3.55 (95% CI: 3.14, 4.01)] are strong predictors for hospitalization. Death occurred in 39 (0.19%) of 20,096 hospitalized children; children with a prior medical condition had an increased odd for death [OR 8.8 (95% CI: 3.7, 21.1)]. Conclusion: Hospitalization and in-hospital death are rare in children diagnosed with COVID-19. However, children at higher risk for these outcomes include those with an underlying medical condition, as well as those of African American descent.
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10.1007/s00431-021-03955-x
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document_parses/pdf_json/a13c282c25408a9dad5cd63a414d7ec265366e48.json
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document_parses/pmc_json/PMC7817069.xml.json
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?:title
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Demographic predictors of hospitalization and mortality in US children with COVID-19
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