|
?:abstract
|
-
SESSION TITLE: Late-breaking Abstract Posters SESSION TYPE: Original Investigation Posters PRESENTED ON: October 18-21, 2020 PURPOSE: The current pandemic of COVID-19 is caused by severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) infection Although clinical data is limited, studies published so far raise concerns about an association between COPD (chronic obstructive pulmonary disease) and worse clinical outcomes in COVID-19 The aim of our study is to determine the association between baseline COPD and outcomes in COVID-19 patients METHODS: A systematic electronic search was performed in PubMed, Embase, and Google Scholar Retrospective studies with original hospitalized COVID-19 patient data were included in our study We used pooled analysis with a random-effects model (Mantel-Haenszel test) to examine the association between COPD and mortality in COVID-19 patients RESULTS: We analyzed 22 studies from 8 countries that included greater than 11,000 patients Mean age of the population was 56 and 58% of the population were male Hypertension was the most prevalent comorbidity in hospitalized COVID-19 patients (42%), followed by diabetes mellitus (23%) COPD was present in 5% of the patients(437/9337) and was associated with higher rates of mortality (OR 3 23, 1 59-6 57;P40 years is estimated to be around >9%) and may reflect greater measures taken by COPD patients to avoid coronavirus exposure Smoking was present in 37% of the patients and interestingly was not associated with higher severity of infection The reason for this is unclear, More randomized studies are needed to assess the relationship between COPD, smoking status and prognosis in COVID-19 patients CLINICAL IMPLICATIONS: This will alert clinicians to the worse prognosis of COVID-19 infection in patients with history of COPD and it will raise a question for future studies to look at the association between baseline COPD and COVID-19 DISCLOSURES: No relevant relationships by Gerard Kiernan, source=Web Response No relevant relationships by Vikramaditya Samala Venkata, source=Web Response
|
![[This page as RDF]](https://research.tib.eu/covid-19/static/rdf-icon.gif){kind=icon}