PropertyValue
?:abstract
  • The current outbreak of SARS-CoV-2 virus has caused a large increase in mortality and morbidity associated with respiratory diseases. Huge efforts are currently ongoing to develop a vaccine against this virus. However, alternative approaches could be considered in the fight against this disease. Among other strategies, structural-based drug design could be an effective approach to generate specific molecules against SARS-CoV-2, thus reducing viral burden in infected patients. Here, in addition to this structural approach, we also revise several therapeutic strategies to fight against this viral threat. Furthermore, we report ACE-2 genetic polymorphic variants affecting residues involved in close contacts with SARS-CoV-2 that might be associated to different infection risks. These analyses could provide valuable information to predict the course of the disease.
is ?:annotates of
?:creator
?:doi
  • 10.3389/fmolb.2020.00204
?:doi
?:journal
  • Front_Mol_Biosci
?:license
  • cc-by
?:pdf_json_files
  • document_parses/pdf_json/c3f3a35a54f4b62097f946476bb1eda7d52b03a4.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7477106.xml.json
?:pmcid
?:pmid
?:pmid
  • 33195397.0
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:sha_id
?:source
  • Medline; PMC
?:title
  • Drug Weaponry to Fight Against SARS-CoV-2
?:type
?:year
  • 2020-08-25

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