PropertyValue
?:abstract
  • A robust supercritical chromatography (SFC) method using an Enantiocel C2-5 column was developed for the multigram separation of the enantiomers of hydroxychloroquine (HCQ), affirming its use as a scalable technology and ability to provide quantities of each enantiomer for clinical evaluation. The enantiomers of HCQ were collected on a gram scale with greater than 99% enantiomeric excess. The S and R enantiomer elution order was confirmed using optical rotation determinations with comparison to previously determined assignments.
is ?:annotates of
?:creator
?:journal
  • J_Chromatogr_A
?:license
  • unk
?:publication_isRelatedTo_Disease
?:source
  • WHO
?:title
  • A preparative chiral separation of hydroxychloroquine using supercritical fluid chromatography
?:type
?:who_covidence_id
  • #893681
?:year
  • 2020

Metadata

Anon_0  
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/net/provenance/ns#DataItem>
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/03/trix/rdfg-1/Graph>
<http://xmlns.com/foaf/0.1/primaryTopic> <https://research.tib.eu/covid-19/entity/ogijl1xp>
<http://xmlns.com/foaf/0.1/topic> Anon_0
<http://www.ontologydesignpatterns.org/cp/owl/informationrealization.owl#realizes> <https://research.tib.eu/covid-19/data/entity/ogijl1xp>
<http://purl.org/net/provenance/ns#createdBy>
Anon_1   (more)
expand all