ohwcjrqt

Property	Value
?:abstract	BACKGROUND AND PURPOSE: In multiple sclerosis (MS), disease-related factors and dysfunctional coping might favor the development of mental distress induced by COVID-19 containment measures. Aim of this study was exploring the relationship between disability, coping strategies, daily life reorganization and neuropsychiatric symptoms in an Italian MS population during the COVID-19 lockdown, in order to identify potentially modifiable factors that could inform clinical management of mental distress in people with MS. METHODS: We explored the relationship between mental distress, disability and coping strategies in the Italian MS population under lockdown. Structural equation modeling was applied to information collected via web survey to identify modifiable factors that could account for mental distress. RESULTS: A total of 845 participants (497 with MS and 348 controls) were included in the study. The MS group had higher scores than the control group for depression (P = 0.005), but not for anxiety, emotional dyscontrol or sleep disturbances. The structural equation modeling explained 74% of the variance observed in depression score. Within the model, three latent factors were characterized from measured variables: motor disability and cognitive dysfunction contributed to disability (ß = 0.509 and ß = 0.836; P < 0.001); positive attitude and exercise contributed to active attitude (ß = 0.386 and ß = 0.297; P < 0.001); and avoidance, social support and watching television contributed to passive attitude (ß = 0.301, ß = 0.243 and ß = 0.212; P < 0.001). With regard to the relationship between latent factors and their influence on depression, disability contributed to passive attitude (ß = 0.855; P < 0.001), while both passive and active attitude significantly influenced depression (ß = 0.729 and ß = -0.456; P < 0.001). CONCLUSION: As a practical implication of our model, favoring exercise would enhance active attitude and its positive impact on mental well-being while, at the same time, reducing the negative impact of disability on depression, representing a valuable tool in facing COVID-19-related mental distress.
is ?:annotates of	<https://research.tib.eu/covid-19/entity/ohwcjrqt_hasAnnotation_C0003467> <https://research.tib.eu/covid-19/entity/ohwcjrqt_hasAnnotation_C0011581> <https://research.tib.eu/covid-19/entity/ohwcjrqt_hasAnnotation_C0037317> <https://research.tib.eu/covid-19/entity/ohwcjrqt_hasAnnotation_C0338656> <https://research.tib.eu/covid-19/entity/ohwcjrqt_hasAnnotation_C1825598> <https://research.tib.eu/covid-19/entity/ohwcjrqt_hasAnnotation_C4285807>
?:creator	<https://research.tib.eu/covid-19/entity/Costabile%2C_T%3B_Carotenuto%2C_A%3B_Lavorgna%2C_L%3B_Borriello%2C_G%3B_Moiola%2C_L%3B_Inglese%2C_M%3B_Petruzzo%2C_M%3B_Trojsi%2C_F%3B_Ianniello%2C_A%3B_Nozzolillo%2C_A%3B_Cellerino%2C_M%3B_Boffa%2C_G%3B_Rosa%2C_L%3B_Servillo%2C_G%3B_Moccia%2C_M%3B_Bonavita%2C_S%3B_Filippi%2C_M%3B_Lanzillo%2C_R%3B_Brescia_Morra%2C_V%3B_Petracca%2C_M> <https://research.tib.eu/covid-19/entity/Costabile%2C_T.%3B_Carotenuto%2C_A.%3B_Lavorgna%2C_L.%3B_Borriello%2C_G.%3B_Moiola%2C_L.%3B_Inglese%2C_M.%3B_Petruzzo%2C_M.%3B_Trojsi%2C_F.%3B_Ianniello%2C_A.%3B_Nozzolillo%2C_A.%3B_Cellerino%2C_M.%3B_Boffa%2C_G.%3B_Rosa%2C_L.%3B_Servillo%2C_G.%3B_Moccia%2C_M.%3B_Bonavita%2C_S.%3B_Filippi%2C_M.%3B_Lanzillo%2C_R.%3B_Morra%2C_V._B.%3B_Petracca%2C_M.>
?:journal	Eur._j._neurol Multiple_Sclerosis_Journal
?:license	unk
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
is ?:relation_isRelatedTo_publication of	<https://research.tib.eu/covid-19/entity/ohwcjrqt_HAS_C1825598_AFFECTS_C0011581> <https://research.tib.eu/covid-19/entity/ohwcjrqt_HAS_C5203670_COEXISTS_WITH_C0026769>
?:source	WHO
?:title	COVID-19 pandemic and mental distress in multiple sclerosis: implications for clinical management
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:who_covidence_id	#1008345 #843544
?:year	2020

Property

Value

?:abstract

BACKGROUND AND PURPOSE: In multiple sclerosis (MS), disease-related factors and dysfunctional coping might favor the development of mental distress induced by COVID-19 containment measures. Aim of this study was exploring the relationship between disability, coping strategies, daily life reorganization and neuropsychiatric symptoms in an Italian MS population during the COVID-19 lockdown, in order to identify potentially modifiable factors that could inform clinical management of mental distress in people with MS. METHODS: We explored the relationship between mental distress, disability and coping strategies in the Italian MS population under lockdown. Structural equation modeling was applied to information collected via web survey to identify modifiable factors that could account for mental distress. RESULTS: A total of 845 participants (497 with MS and 348 controls) were included in the study. The MS group had higher scores than the control group for depression (P = 0.005), but not for anxiety, emotional dyscontrol or sleep disturbances. The structural equation modeling explained 74% of the variance observed in depression score. Within the model, three latent factors were characterized from measured variables: motor disability and cognitive dysfunction contributed to disability (ß = 0.509 and ß = 0.836; P < 0.001); positive attitude and exercise contributed to active attitude (ß = 0.386 and ß = 0.297; P < 0.001); and avoidance, social support and watching television contributed to passive attitude (ß = 0.301, ß = 0.243 and ß = 0.212; P < 0.001). With regard to the relationship between latent factors and their influence on depression, disability contributed to passive attitude (ß = 0.855; P < 0.001), while both passive and active attitude significantly influenced depression (ß = 0.729 and ß = -0.456; P < 0.001). CONCLUSION: As a practical implication of our model, favoring exercise would enhance active attitude and its positive impact on mental well-being while, at the same time, reducing the negative impact of disability on depression, representing a valuable tool in facing COVID-19-related mental distress.

is ?:annotates of