PropertyValue
?:abstract
  • The researcher community across the globe is on a search for a promising animal model that closely mimics the clinical manifestation of SARS-CoV-2. Though some developments were seen such as serial adaptation in various animal species or the creation of genetically engineered models, a suitable animal model remains elusive. A model that could display the severity of human illness and can be used for the fast-track evaluation of potential drugs as well as for the clinical trials of vaccines is an urgent need of the hour. In the light of huge information generated on SARS-CoV-2 and daily updates received from the research community, we have chosen to review the current status of animal models of SARS-CoV-2 in encompassing the areas of viral replication, transmission, active/passive immunization, clinical disease, and pathology. The review is intended to help the researchers in the selection of appropriate animal models for SARS CoV-2 research in the fight against the current global pandemic.
is ?:annotates of
?:creator
?:journal
  • Virusdisease
?:license
  • unk
?:publication_isRelatedTo_Disease
?:source
  • WHO
?:title
  • Selection of animal models for COVID-19 research
?:type
?:who_covidence_id
  • #962162
?:year
  • 2020

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