PropertyValue
?:abstract
  • We are presenting our on going studies with inhibitory research on Tmprss2, S-protein:Ace2, and 3CLpro using compound screening coupled with X-ray crystallography, molecular modeling, live virus screening using host human cells (BSL3 facility at UC Center for Infectious Disease and Vector Research, and organ-on-a-chiat Harvard Medical School for safety profiling before proceeding to animal models with InVivo BioSystems for ADMET brdivWe have derived a useful chemical toolkit of 350 compounds for the community to study with biochemical assays and other biophysical-chemical studies that will prove useful in searching for optimal inhibitors of these targets to find suitable pharmacophores for blocking each of these enzyme\'s activities -- that would be beneficial for human health Our past successes with these methodologies have resulted in over 28 patents, 11 technologies and two startucompanies /div
is ?:annotates of
?:creator
?:license
  • unk
?:publication_isRelatedTo_Disease
?:source
  • WHO
?:title
  • Attacking COVID-19 Progression using Multi-Drug Therapy for Synergetic Target Engagement
?:type
?:who_covidence_id
  • #227
?:year
  • 2020

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