|
?:abstract
|
-
BACKGROUND The role of SARS-CoV-2 as the cause of chilblains in children remains a matter of debate, but important to elucidate for patient isolation and contact tracing. We sought to define the etiology, clinical presentation, time course and outcomes of children presenting to the Emergency Department (ED) with cutaneous manifestations shortly after the first pandemic peak of COVID-19 in Spain. METHODS Prospective, observational study in children <15 years of age evaluated for skin lesions in the ED of three pediatric hospitals. Children underwent a comprehensive work-up including SARS-CoV-2 antibodies and PCR, and serology and PCR tests for other viruses and bacteria. A one-month follow-up visit was conducted. RESULTS From April 14 through May 8, 2020 we enrolled 62 children. Of those 34 had acro-ischemic skin lesions and 28 a variety of skin rashes. Overall 40% of children had mild systemic symptoms. Children with chilblains were older, had pain more frequently and more prolonged duration of skin lesions, while those with non-specific rashes had fever more frequently. Lesions were resolved in 75% of children at follow-up. Five patients demonstrated SARS-CoV-2 antibodies, and none tested positive by PCR. Three additional patients tested positive by PCR for rhinovirus, M. pneumoniae and C. pneumoniae. CONCLUSIONS The number of ED visits for chilblains, which are rare in pediatrics, was high soon after the first peak of COVID-19 in Spain. The disease course was self-limited, outcomes were favorable and the possibility of viral transmission was negligible as all patients tested negative for SARS-CoV-2 by PCR.
|
![[This page as RDF]](https://research.tib.eu/covid-19/static/rdf-icon.gif){kind=icon}