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Results of three rapid immunochromatographic tests (ICTs) were compared with those obtained with two automated immunoassays for evaluation of their usefulness. One hundred fifty-nine patients and 67 healthy volunteers were included. Different assays demonstrate 41–45% of diagnostic sensitivities and 91–98% of specificities, with substantial agreement (89.3–91.2%), but a high percentage of weak positive results (13–22%) was observed with ICTs. ICTs performances were comparable to those of automated immunoassays. ICTs could have a role as screening approach due to their easy usability. Subjective interpretation, significant rate of uncertain results, uncertainty on viral antigens source are undoubtedly drawbacks.
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?:doi
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10.1007/s10096-020-04040-1
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Eur_J_Clin_Microbiol_Infect_Dis
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document_parses/pdf_json/53773ae9338764659ce15c3a611d68cff79f782a.json
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document_parses/pmc_json/PMC7572234.xml.json
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?:title
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Evaluation of three immunochromatographic tests in COVID-19 serologic diagnosis and their clinical usefulness
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