PropertyValue
?:abstract
  • Several drugs have been developed for the treatment of severe acute respiratory syndrome coronavirus (SARS-CoV) using different protocols;however, some methods use different reagents that are dangerous and require special conditions The objective of this research was to synthesize a Lactam-steroid derivative to evaluate its theoretical interaction with SARS-CoV using at 6LU7-protein as a theoretical model Furthermore, this interaction was carried out in a docking model using hydroxychloroquine and favipiravir as controls The results showed that the binding energy involved in the interaction of the lactam-steroid derivative with 6LU7 protein surface was lower compared with both hydroxychloroquine and favipiravir In conclusion, the lactam-steroid derivative could be an alternative therapeutic to treatment of SARS-CoV
is ?:annotates of
?:creator
?:journal
  • Biointerface_Research_in_Applied_Chemistry
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Design and Synthesis of a Lactam-Steroid Derivative and their Theoretical Interaction with a SAR-COV2
?:type
?:who_covidence_id
  • #809514

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