PropertyValue
?:abstract
  • The need to identify and effectively treat COVID-19 cases at highest risk for severe disease is critical. We identified seven common genetic variants (three novel) that modulate COVID-19 susceptibility and severity, implicating IFNAR2, CCHCR1, TCF19, SLC6A20 and the hyaluronan pathway as potential therapeutic targets. A high genetic burden was strongly associated with increased risk of hospitalization and severe disease among COVID-19 cases, especially among individuals with few known risk factors.
is ?:annotates of
?:creator
?:doi
?:doi
  • 10.1101/2020.12.14.20248176
?:license
  • medrxiv
?:pdf_json_files
  • document_parses/pdf_json/052637eb79f9186719296699c7787f3e69bdd98b.json
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • MedRxiv; WHO
?:title
  • Common genetic variants identify therapeutic targets for COVID-19 and individuals at high risk of severe disease
?:type
?:year
  • 2020-12-16

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