PropertyValue
?:abstract
  • COVID-19 is a viral disease caused by SARS-CoV-2 that compromises the host immune response in severe cases, promoting a hyperinflammation that results in acute lung injury and multiple organs failure. In this context, patients presenting with immune-related diseases, such as Crohn\'s disease, affected by COVID-19, may have an uncertain prognosis. We report on a case of a young female patient with a severe Crohn\'s disease that presented with COVID-19 pneumonia and a favorable outcome even maintaining the use of adalimumab, TNF - alpha inhibitor and prednisone. This case raises the hypothesis that aside from prednisone, TNF-α inhibitors such as adalimumab could be used to stop the progression to COVID-19 complications by blocking the TNF-alpha-driven inflammatory process that occurs in severe COVID-19.
is ?:annotates of
?:creator
?:journal
  • Rev_Inst_Med_Trop_Sao_Paulo
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Favorable outcome of COVID-19 in a young woman with severe Crohn\'s disease on regular use of adalimumab and prednisone: a case report
?:type
?:who_covidence_id
  • #983846
?:year
  • 2020

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