qy7xba28

Property	Value
?:abstract	BACKGROUND: SARS-CoV-2 infection among People Living With HIV (PLWH) is not well-described. OBJECTIVE: To study COVID-19 symptoms and SARS-CoV-2 PCR-based swab testing among participants of the Multicenter AIDS Cohort Study (MACS) and Women’s Interagency HIV Study (WIHS). METHODS: A telephone survey was collected April-June 30, 2020. Symptom and testing prevalence were explored. Multivariable logistic regression was used to examine the factors associated with SARS-CoV-2 positivity. RESULTS: The survey was completed by 3411 participants, including 2078 (61%) PLWH and 1333 HIV-seronegative (SN) participants from across the US. Thirteen percent (n = 441) were tested for SARS-CoV-2 infection (13.4% of PLWH vs 12.2% of SN). Among those tested, positivity was higher in PLWH than SN (11.2% vs 6.1%, p = 0.08). Reasons for not being tested included testing not being available (30% of participants) and not knowing where to get tested (16% of participants). Most symptoms reported since January 2020 were similar in PLWH and SN, including headache (23% vs. 24%), myalgias (19% vs 18%), shortness of breath (14% vs 13%), chills (12% vs 10%), fever (6% vs 6%) and loss of taste or smell (6% vs 7%). Among PLWH who tested positive for SARS-CoV-2 DNA, the most common symptoms were headache (71%), myalgia (68%), cough (68%) and chills (65%). In multivariable analysis among those tested, the odds of SARS-CoV-2 positivity were higher among PLWH than SN (aOR = 2.22 95%CI = 01.01–4.85, p = 0.046) and among those living with others versus living alone (aOR = 2.95 95%CI = 1.18–7.40). CONCLUSION: Prevalence and type of COVID-19 symptoms were similar in PLWH and SN. SARS-CoV-2 infection may be elevated among PLWH.
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?:creator	<https://research.tib.eu/covid-19/entity/D%E2%80%99Souza%2C_Gypsyamber%3B_Springer%2C_Gayle%3B_Gustafson%2C_Deborah%3B_Kassaye%2C_Seble%3B_Alcaide%2C_Maria_L.%3B_Ramirez%2C_Catalina%3B_Sharma%2C_Anjali%3B_Palella%2C_Frank_J.%3B_Tien%2C_Phyllis_C.%3B_Detels%2C_Roger%3B_Kempf%2C_Mirjam-Colette%3B_Lahiri%2C_Cecile_D.%3B_Rinaldo%2C_Charles_R.%3B_French%2C_Audrey_L.%3B_Margolick%2C_Joseph_B.%3B_Adimora%2C_Ada_A.>
?:doi	<https://research.tib.eu/covid-19/entity/10.1080/25787489.2020.1844521>
?:doi	10.1080/25787489.2020.1844521
?:journal	HIV_research_&_clinical_practice
?:license	no-cc
?:pdf_json_files	document_parses/pdf_json/cd121c3fda2579b2146b9cf45c48c7fb749b7bd2.json
?:pmc_json_files	document_parses/pmc_json/PMC7682380.xml.json
?:pmcid	<https://research.tib.eu/covid-19/entity/PMC7682380>
?:pmid	<https://research.tib.eu/covid-19/entity/33211636.0>
?:pmid	33211636.0
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
?:sha_id	<https://research.tib.eu/covid-19/entity/cd121c3fda2579b2146b9cf45c48c7fb749b7bd2>
?:source	Medline; PMC
?:title	COVID-19 symptoms and SARS-CoV-2 infection among people living with HIV in the US: the MACS/WIHS combined cohort study
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:year	2020-11-19

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Value

?:abstract

BACKGROUND: SARS-CoV-2 infection among People Living With HIV (PLWH) is not well-described. OBJECTIVE: To study COVID-19 symptoms and SARS-CoV-2 PCR-based swab testing among participants of the Multicenter AIDS Cohort Study (MACS) and Women’s Interagency HIV Study (WIHS). METHODS: A telephone survey was collected April-June 30, 2020. Symptom and testing prevalence were explored. Multivariable logistic regression was used to examine the factors associated with SARS-CoV-2 positivity. RESULTS: The survey was completed by 3411 participants, including 2078 (61%) PLWH and 1333 HIV-seronegative (SN) participants from across the US. Thirteen percent (n = 441) were tested for SARS-CoV-2 infection (13.4% of PLWH vs 12.2% of SN). Among those tested, positivity was higher in PLWH than SN (11.2% vs 6.1%, p = 0.08). Reasons for not being tested included testing not being available (30% of participants) and not knowing where to get tested (16% of participants). Most symptoms reported since January 2020 were similar in PLWH and SN, including headache (23% vs. 24%), myalgias (19% vs 18%), shortness of breath (14% vs 13%), chills (12% vs 10%), fever (6% vs 6%) and loss of taste or smell (6% vs 7%). Among PLWH who tested positive for SARS-CoV-2 DNA, the most common symptoms were headache (71%), myalgia (68%), cough (68%) and chills (65%). In multivariable analysis among those tested, the odds of SARS-CoV-2 positivity were higher among PLWH than SN (aOR = 2.22 95%CI = 01.01–4.85, p = 0.046) and among those living with others versus living alone (aOR = 2.95 95%CI = 1.18–7.40). CONCLUSION: Prevalence and type of COVID-19 symptoms were similar in PLWH and SN. SARS-CoV-2 infection may be elevated among PLWH.

is ?:annotates of