r7zhoi25

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?:abstract	BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a current pandemic worldwide. This virus can reach all organs and disturbs the immune system, leading to a cytokine storm in severe forms. We aimed to report cutaneous features among coronavirus disease 2019 (COVID-19) hospitalized patients. METHODS: We performed a cross-sectional study on 1 given day among all patients hospitalized in acute care for COVID-19 and included all patients with cutaneous features. Follow-up 48 hours later was obtained. RESULTS: Among 59 adult patients hospitalized on the day of the study in an infectious diseases ward for SARS-CoV-2 infection who were confirmed by molecular assay and/or radiological findings (computed tomography scan), 40 were included. Several cutaneous manifestations were found: macular exanthema (80%), face edema (32%), livedo (13%), urticarial rash (8%), purpura (5%), oral lichenoid lesions (33%), and conjunctivitis (18%). Cutaneous biopsy was performed in 17 patients. Histological findings showed mast cell hyperplasia (100%), superficial perivascular infiltrate of lymphocytes (94%), and superficial edema (47%) consistent with capillary leak. CONCLUSIONS: Various dermatological signs can be encountered during COVID-19. A macular rash was the most frequent. All cutaneous features could be related to a vascular leak process.
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?:creator	<https://research.tib.eu/covid-19/entity/Mascitti%2C_H%C3%A9l%C3%A8ne%3B_Bonsang%2C_Benjamin%3B_Dinh%2C_Aur%C3%A9lien%3B_Assan%2C_Florence%3B_Perronne%2C_V%C3%A9ronique%3B_Leblanc%2C_Thibault%3B_Duran%2C_Clara%3B_Bouchand%2C_Fr%C3%A9d%C3%A9rique%3B_Matt%2C_Morgan%3B_Le_Gal%2C_Aur%C3%A9lie%3B_N%E2%80%99guyen_Van_Thanh%2C_Julia%3B_Lanore%2C_Aymeric%3B_Jacob%2C_Louis%3B_Kiavue%2C_Nicolas%3B_Sim%C3%A9on%2C_Soline%3B_Bessis%2C_Simon%3B_de_Truchis%2C_Pierre%3B_Landowski%2C_St%C3%A9phanie%3B_Davido%2C_Benjamin%3B_Moreau%2C_Fr%C3%A9d%C3%A9rique%3B_Rameix-Welti%2C_Marie-Anne%3B_Gault%2C_Elyanne%3B_Gaillard%2C_Jean-Louis%3B_Roux%2C_Anne-Laure%3B_Sivadon-Tardy%2C_Val%C3%A9rie%3B_Salomon%2C_Elsa%3B_El_Sayed%2C_Faten%3B_Carlier%2C_Robert%3B_Emile%2C_Jean-Fran%C3%A7ois%3B_Perronne%2C_Christian%3B_Bourgault-Villada%2C_Isabelle>
?:doi	10.1093/ofid/ofaa394
?:doi	<https://research.tib.eu/covid-19/entity/10.1093/ofid/ofaa394>
?:journal	Open_Forum_Infect_Dis
?:license	cc-by-nc-nd
?:pdf_json_files	document_parses/pdf_json/ba8f108b12129e557260d1def55e6624c8dba0c6.json
?:pmc_json_files	document_parses/pmc_json/PMC7650967.xml.json
?:pmcid	<https://research.tib.eu/covid-19/entity/PMC7650967>
?:pmid	<https://research.tib.eu/covid-19/entity/33204745.0>
?:pmid	33204745.0
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
is ?:relation_isRelatedTo_publication of	<https://research.tib.eu/covid-19/entity/r7zhoi25_HAS_C0042776_CAUSES_C0919747>
?:sha_id	<https://research.tib.eu/covid-19/entity/ba8f108b12129e557260d1def55e6624c8dba0c6>
?:source	Medline; PMC
?:title	Clinical Cutaneous Features of Patients Infected With SARS-CoV-2 Hospitalized for Pneumonia: A Cross-sectional Study
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:year	2020-10-18

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Value

?:abstract

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a current pandemic worldwide. This virus can reach all organs and disturbs the immune system, leading to a cytokine storm in severe forms. We aimed to report cutaneous features among coronavirus disease 2019 (COVID-19) hospitalized patients. METHODS: We performed a cross-sectional study on 1 given day among all patients hospitalized in acute care for COVID-19 and included all patients with cutaneous features. Follow-up 48 hours later was obtained. RESULTS: Among 59 adult patients hospitalized on the day of the study in an infectious diseases ward for SARS-CoV-2 infection who were confirmed by molecular assay and/or radiological findings (computed tomography scan), 40 were included. Several cutaneous manifestations were found: macular exanthema (80%), face edema (32%), livedo (13%), urticarial rash (8%), purpura (5%), oral lichenoid lesions (33%), and conjunctivitis (18%). Cutaneous biopsy was performed in 17 patients. Histological findings showed mast cell hyperplasia (100%), superficial perivascular infiltrate of lymphocytes (94%), and superficial edema (47%) consistent with capillary leak. CONCLUSIONS: Various dermatological signs can be encountered during COVID-19. A macular rash was the most frequent. All cutaneous features could be related to a vascular leak process.

is ?:annotates of