PropertyValue
?:abstract
  • In many different infectious syndromes, most notably several viral conditions, time to therapy initiation from symptom onset has been identified as a critical component contributing to the success of therapy. With regards to COVID-19, several therapeutic antivirals, both repurposed and novel, have been evaluated for overall safety and efficacy. As the literature related to these therapies has expanded over the last several months, a wide array of trial designs, time to therapy initiation thresholds, and clinical outcomes with regards to time to initiation have been reported. Herein we describe the potential impact of time to therapy initiation on outcomes in patients with COVID-19 and detail the existing data surrounding this topic in relation to remdesivir, convalescent plasma, lopinavir/ritonavir, and hydroxychloroquine.
is ?:annotates of
?:creator
?:doi
  • 10.1016/j.mayocpiqo.2020.09.010
?:doi
?:journal
  • Mayo_Clin_Proc_Innov_Qual_Outcomes
?:license
  • els-covid
?:pdf_json_files
  • document_parses/pdf_json/559cc59e025bec73f45eaf20d6a0fe980f9f4840.json
?:pmcid
?:pmid
?:pmid
  • 33073177.0
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:sha_id
?:source
  • Elsevier; Medline; PMC
?:title
  • Time to Treat: Applying Lessons Learned from Other Viral Syndromes to SARS-CoV-2
?:type
?:year
  • 2020-10-12

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