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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the global coronavirus disease 2019 (COVID-19) outbreak. Along with the respiratory tract, the gastrointestinal (GI) tract is one of the main extra-pulmonary targets of SARS-CoV-2 with respect to symptom occurrence and is a potential route for virus transmission, most likely due to the presence of angiotensin-converting enzyme 2. Therefore, understanding the mechanisms of GI injury is crucial for a harmonized therapeutic strategy against COVID-19. This review summarizes the current evidence for the clinical features of and possible pathogenic mechanisms leading to GI injury in COVID-19.
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document_parses/pdf_json/b9fe5c94d047a29a9b4ce1c21eb31142eff0dcf0.json
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document_parses/pmc_json/PMC7696882.xml.json
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Clinical Features and Pathogenic Mechanisms of Gastrointestinal Injury in COVID-19
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