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?:abstract
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases were first reported in Wuhan, Hubei province of China in December, 2019 SARS- COV-2 primarily affects the cardio-respiratory system Over the last few months, several studies have described various neurological sequelae of SARS-COV-2 infection Neurological complications are more frequent in patients with severe respiratory infections In this review, we have analyzed the current literature on neuromuscular complications associated with SARS-COV-2 and highlighted possible mechanisms of neuromuscular invasion We reviewed 11 studies describing 11 cases of Guillain Barre syndrome (GBS), and 1 case each of Miller Fisher syndrome, Polyneuritis Cranialis, Acute myelitis, Oculomotor paralysis and Bell\'s Palsy associated with SARS-COV-2 infection Mean age of patients with GBS was 61 54 years, with standard deviation (SD) 14 18 years Majority patients had fever and cough as the first symptom of SARS COV-2 infection Mean time for onset of neurological symptoms from initial symptoms in 11 patients was 8 18 days, with SD of 2 86 days Mean time to performing electrodiagnostic study from onset of neurological symptom was 6 days with standard deviation of 3 25 Six patients had demyelinating pattern, three had acute sensory motor axonal neuropathy, and one had acute motor axonal neuropathy on electrodiagnostic studies
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