sorcgdsy

Property	Value
?:abstract	Towards the end of 2019, new coronavirus causing acute respiratory distress syndrome in patients was detected in Wuhan Province, China This virus was called serious acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the International Virus Taxonomy Committee The disease caused by this new coronavirus was called coronavirus disease-2019 (COVID-19) by the World Health Organization This virus was found to be in the subclass of Betakoronavirus caused by bats The role of viral proteins such as envelopes, membranes, nucleocapsids and spike proteins responsible for viral infectivity in immunopathogenesis is being investigated in studies It has been emphasized in studies in which multiple organ failure develops due to the development of cytokine storm, especially in the advanced stages of the disease An effective host immune response, including natural and adaptive immunity to SARS-Cov-2, is essential for controlling and treating viral infection Although there is no effective treatment for the disease today, the benefits of various immunosuppressive and immunomodulatory drugs have been shown in studies In this article, the immunopathogenesis of SARS-CoV-2 and the treatment models that can be effective on immunopathogenesis are reviewed in the light of curr ent literature (English) [ABSTRACT FROM AUTHOR] 2019\'un sonlarına doğru, Çin\'in Wuhan Eyaletinde hastalarda akut solunum sıkıntısı sendromuna neden olan yeni koronavirüs tespit edildi Bu virüse, Uluslararası Virüs Taksonomi Komitesi tarafından ciddi akut solunum sendromu koronavirüs 2 (SARS-CoV-2) adı verildi Bu yeni koronavirüsün neden olduğu hastalığa ise Dünya Sağlık Örgütü tarafından koronavirüs hastalığı-2019 (COVID-19) adı verildi Bu virüsün yarasalardan kaynaklanan Betakoronavirus alt sınıfında olduğu belirlenmiştir Viral enfektiviteden sorumlu zarf, membran, nükleokapsid ve spike proteinleri gibi viral proteinlerin immünopatogenezdeki rolü çalışmalarda araştırılmaktadır Özellikle hastalığın ileri evrelerinde sitokin fırtınası gelişimine bağlı çoklu organ yetmezliklerinin geliştiği çalışmalarda vurgulanmıştır SARS-CoV-2\'ye karşı doğal ve adaptif bağışıklık da dahil olmak üzere etkin konakçı bağışıklık yanıtı viral enfeksiyonu kontrol etmek ve tedavi için çok önemlidir Günümüzde hastalıkta etkili bir tedavi bulunamamakla beraber çalışmalarda çeşitli immünsupresif ve immunmodülatör özelliği olan bazı ilaçların faydası gösterilmiştir Bu yazıda SARSCoV- 2\'nin immunopatogezi ve bunun üzerinden etkili olabilecek tedavi modelleri, güncel literatür eşliğinde gözden geçirilmiştir (Turkish) [ABSTRACT FROM AUTHOR] Copyright of Selcuk University Medical Journal is the property of Selcuk University Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder\'s express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )
is ?:annotates of	<https://research.tib.eu/covid-19/entity/sorcgdsy_hasAnnotation_C0013227> <https://research.tib.eu/covid-19/entity/sorcgdsy_hasAnnotation_C0026766> <https://research.tib.eu/covid-19/entity/sorcgdsy_hasAnnotation_C0042776> <https://research.tib.eu/covid-19/entity/sorcgdsy_hasAnnotation_C0270602> <https://research.tib.eu/covid-19/entity/sorcgdsy_hasAnnotation_C1175743> <https://research.tib.eu/covid-19/entity/sorcgdsy_hasAnnotation_C1266129> <https://research.tib.eu/covid-19/entity/sorcgdsy_hasAnnotation_C1416578> <https://research.tib.eu/covid-19/entity/sorcgdsy_hasAnnotation_C3889152> <https://research.tib.eu/covid-19/entity/sorcgdsy_hasAnnotation_C5203676>
?:creator	<https://research.tib.eu/covid-19/entity/Atay%2C_%C3%96zge_Asilsoy%3B_Suna%2C>
?:journal	Selcuk_University_Medical_Journal
?:license	unk
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
is ?:relation_isRelatedTo_publication of	<https://research.tib.eu/covid-19/entity/sorcgdsy_HAS_C0178774_ASSOCIATED_WITH_C0026766> <https://research.tib.eu/covid-19/entity/sorcgdsy_HAS_C0206750_CAUSES_C0035222> <https://research.tib.eu/covid-19/entity/sorcgdsy_HAS_C0700271_ASSOCIATED_WITH_C0026766>
?:source	WHO
?:title	SARS-Cov-2 Ímmunopatogenezi ve Olası Antiinflamatuvar Tedavi Seçenekleri
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:who_covidence_id	#822306
?:year	2020

Property

Value

?:abstract

Towards the end of 2019, new coronavirus causing acute respiratory distress syndrome in patients was detected in Wuhan Province, China This virus was called serious acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the International Virus Taxonomy Committee The disease caused by this new coronavirus was called coronavirus disease-2019 (COVID-19) by the World Health Organization This virus was found to be in the subclass of Betakoronavirus caused by bats The role of viral proteins such as envelopes, membranes, nucleocapsids and spike proteins responsible for viral infectivity in immunopathogenesis is being investigated in studies It has been emphasized in studies in which multiple organ failure develops due to the development of cytokine storm, especially in the advanced stages of the disease An effective host immune response, including natural and adaptive immunity to SARS-Cov-2, is essential for controlling and treating viral infection Although there is no effective treatment for the disease today, the benefits of various immunosuppressive and immunomodulatory drugs have been shown in studies In this article, the immunopathogenesis of SARS-CoV-2 and the treatment models that can be effective on immunopathogenesis are reviewed in the light of curr ent literature (English) [ABSTRACT FROM AUTHOR] 2019\'un sonlarına doğru, Çin\'in Wuhan Eyaletinde hastalarda akut solunum sıkıntısı sendromuna neden olan yeni koronavirüs tespit edildi Bu virüse, Uluslararası Virüs Taksonomi Komitesi tarafından ciddi akut solunum sendromu koronavirüs 2 (SARS-CoV-2) adı verildi Bu yeni koronavirüsün neden olduğu hastalığa ise Dünya Sağlık Örgütü tarafından koronavirüs hastalığı-2019 (COVID-19) adı verildi Bu virüsün yarasalardan kaynaklanan Betakoronavirus alt sınıfında olduğu belirlenmiştir Viral enfektiviteden sorumlu zarf, membran, nükleokapsid ve spike proteinleri gibi viral proteinlerin immünopatogenezdeki rolü çalışmalarda araştırılmaktadır Özellikle hastalığın ileri evrelerinde sitokin fırtınası gelişimine bağlı çoklu organ yetmezliklerinin geliştiği çalışmalarda vurgulanmıştır SARS-CoV-2\'ye karşı doğal ve adaptif bağışıklık da dahil olmak üzere etkin konakçı bağışıklık yanıtı viral enfeksiyonu kontrol etmek ve tedavi için çok önemlidir Günümüzde hastalıkta etkili bir tedavi bulunamamakla beraber çalışmalarda çeşitli immünsupresif ve immunmodülatör özelliği olan bazı ilaçların faydası gösterilmiştir Bu yazıda SARSCoV- 2\'nin immunopatogezi ve bunun üzerinden etkili olabilecek tedavi modelleri, güncel literatür eşliğinde gözden geçirilmiştir (Turkish) [ABSTRACT FROM AUTHOR] Copyright of Selcuk University Medical Journal is the property of Selcuk University Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder\'s express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )

is ?:annotates of