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?:abstract
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Objectives: During the 2019 Coronavirus disease (COVID-19) outbreak, malnutrition may contribute to COVID-19 adverse outcomes We conducted a clinical epidemiological analysis to investigate the association of malnutrition with hospitalized duration in patients with COVID-19 Design: Retrospective survey study Setting: Taikang Tongji (Wuhan) hospital in Wuhan, China Participants: 139 patients with COVID-19 Methods: In total, 139 patients with COVID-19 from patients in the Infection Department of Taikang Tongji (Wuhan) hospital from February 2020 to April 2020 were analyzed retrospectively We used the “Global leadership Initiative on Malnutrition(GLIM)” assessment standard published in 2019 to assess nutritional status Prolonged hospitalization was lasting more than the median value of the hospitalized days (17 days) in this population Results: According to the assessment results of GLIM nutrition assessment, the patients were divided into malnutrition group and normal nutrition group Compared with the patients in the normal nutrition group, the hospitalization time was longer(15 67±6 26 days versus 27 48±5 04 days, P = 0 001) Kaplan-Meier analysis showed patients with malnutrition were more likely to be hospitalized longer compared with those normal nutrition (mean with 95% confidence interval [CI]: 28 91[27 52–30 30] versus 22 78[21 76–23 79], P = 0 001) COX regression analysis showed that malnutrition (hazard ratio [HR] = 3 773, P for trend = 0 001) was proportional associated with being discharged from hospital delayed Conclusion and implications: Present findings suggested that malnutrition contributed to predicting a probability of prolonged hospitalization in patients with COVID-19 infection, to whom extra attentions and precautions should be paid during clinical treatments Based on the existing results, it is recommended that inpatients with nutritional risk or malnutrition start nutritional support treatment as soon as possible © 2020, Serdi and Springer-Verlag International SAS, part of Springer Nature
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