?:abstract
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The COVID-19 pandemic increased the demand for neuromuscular blocking agents for critically ill patients requiring mechanical ventilation, leading to a shortage of the neuromuscular blocking agents vecuronium and rocuronium To assure continued availability of these two critically important drugs, the FDA is permitting the temporary manufacture of these drugs without the vial cap (seal) incorporating the warning, \'Paralyzing Agent,\' normally required by USP and the FDA Supply constraints prevented manufacturers from obtaining the products with the usual warning statements on the vial cap in time to address the shortage This temporary situation has obvious safety implications because the absence of warning may make the vials look more like other medications with similar size vials and cap colors
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