PropertyValue
?:abstract
  • Coronavirus is one of the causative agents for multiple human respiratory illnesses A novel coronavirus, similar to the one that caused severe acute respiratory syndrome (SARS) in 2003, was identified as the cause of the current pandemic of coronavirus disease (COVID-19), which was first reported in late December 2019 in Wuhan, China Since then, this novel coronavirus has spread across the globe, with most identified COVID-19 cases and fatalities occurring in the United States In this Perspective, we discuss coronavirus pathogenicity, conventional antiviral therapies, prophylactic strategies, and novel treatment strategies for COVID-19 We highlight the application of CRISPR technology as an emerging pan-antiviral therapy We also discuss the challenges of in vivo delivery of CRISPR components and propose novel approaches to achieve selective delivery exclusively into SARS-CoV-2-infected cells with high efficiency by hijacking the surface proteins of SARS-CoV-2
is ?:annotates of
?:creator
?:journal
  • ACS_Pharmacol_Transl_Sci
?:license
  • unk
?:publication_isRelatedTo_Disease
?:source
  • WHO
?:title
  • Double-Barreled CRISPR Technology as a Novel Treatment Strategy For COVID-19
?:type
?:who_covidence_id
  • #872644
?:year
  • 2020

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