toj7vzx5

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?:abstract	BACKGROUND: Men who contract coronavirus disease 2019 (COVID-19) appear to have worse clinical outcomes compared with women which raises the possibility of androgen-dependent effects. AIM: We sought to determine if testosterone replacement therapy (TRT) is associated with worse clinical outcomes. METHODS: Through a retrospective chart review, we identified 32 men diagnosed with COVID-19 and on TRT. They were propensity score matched to 63 men diagnosed with COVID-19 and not on TRT. Data regarding comorbidities and endpoints such as hospital admission, intensive care unit admission, ventilator utilization, thromboembolic events, and death were extracted. Chi-square and Kruskal-Wallis tests examined differences in categorical and continuous variables, respectively. Logistic regression analysis tested the relationship between TRT status and the study endpoints. RESULTS: There were no statistically significant differences between the 2 groups, and TRT was not a predictor of any of the endpoints on multivariate analysis. CONCLUSION: These results suggest that TRT is not associated with a worse clinical outcome in men diagnosed with COVID-19. Rambhatla A, Bronkema CJ, Corsi N, et al. COVID-19 Infection in Men on Testosterone Replacement Therapy. J Sex Med 2020;XX:XXX-XXX. Background: Men who contract coronavirus disease 2019 (COVID-19) appear to have worse clinical outcomes compared with women which raises the possibility of androgen-dependent effects Aim: We sought to determine if testosterone replacement therapy (TRT) is associated with worse clinical outcomes Methods: Through a retrospective chart review, we identified 32 men diagnosed with COVID-19 and on TRT They were propensity score matched to 63 men diagnosed with COVID-19 and not on TRT Data regarding comorbidities and endpoints such as hospital admission, intensive care unit admission, ventilator utilization, thromboembolic events, and death were extracted Chi-square and Kruskal-Wallis tests examined differences in categorical and continuous variables, respectively Logistic regression analysis tested the relationship between TRT status and the study endpoints Results: There were no statistically significant differences between the 2 groups, and TRT was not a predictor of any of the endpoints on multivariate analysis Conclusion: These results suggest that TRT is not associated with a worse clinical outcome in men diagnosed with COVID-19 Copyright (C) 2020, International Society for Sexual Medicine Published by Elsevier Inc All rights reserved
is ?:annotates of	<https://research.tib.eu/covid-19/entity/toj7vzx5_hasAnnotation_C0040038> <https://research.tib.eu/covid-19/entity/toj7vzx5_hasAnnotation_C1419866>
?:creator	<https://research.tib.eu/covid-19/entity/Rambhatla%2C_A.%3B_Bronkema%2C_C._J.%3B_Corsi%2C_N.%3B_Keeley%2C_J.%3B_Sood%2C_A.%3B_Affas%2C_Z.%3B_Dabaja%2C_A._A.%3B_Rogers%2C_C._G.%3B_Liroff%2C_S._A.%3B_Abdollah%2C_F.> <https://research.tib.eu/covid-19/entity/Rambhatla%2C_Amarnath%3B_Bronkema%2C_Chandler_J%3B_Corsi%2C_Nicholas%3B_Keeley%2C_Jacob%3B_Sood%2C_Akshay%3B_Affas%2C_Ziad%3B_Dabaja%2C_Ali_A%3B_Rogers%2C_Craig_G%3B_Liroff%2C_Stephen_A%3B_Abdollah%2C_Firas>
?:journal	J._sex._med Journal_of_Sexual_Medicine
?:license	unk
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
?:source	WHO
?:title	COVID-19 Infection in Men on Testosterone Replacement Therapy
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:who_covidence_id	#1065396 #943397
?:year	2020 2021

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?:abstract

BACKGROUND: Men who contract coronavirus disease 2019 (COVID-19) appear to have worse clinical outcomes compared with women which raises the possibility of androgen-dependent effects. AIM: We sought to determine if testosterone replacement therapy (TRT) is associated with worse clinical outcomes. METHODS: Through a retrospective chart review, we identified 32 men diagnosed with COVID-19 and on TRT. They were propensity score matched to 63 men diagnosed with COVID-19 and not on TRT. Data regarding comorbidities and endpoints such as hospital admission, intensive care unit admission, ventilator utilization, thromboembolic events, and death were extracted. Chi-square and Kruskal-Wallis tests examined differences in categorical and continuous variables, respectively. Logistic regression analysis tested the relationship between TRT status and the study endpoints. RESULTS: There were no statistically significant differences between the 2 groups, and TRT was not a predictor of any of the endpoints on multivariate analysis. CONCLUSION: These results suggest that TRT is not associated with a worse clinical outcome in men diagnosed with COVID-19. Rambhatla A, Bronkema CJ, Corsi N, et al. COVID-19 Infection in Men on Testosterone Replacement Therapy. J Sex Med 2020;XX:XXX-XXX.
Background: Men who contract coronavirus disease 2019 (COVID-19) appear to have worse clinical outcomes compared with women which raises the possibility of androgen-dependent effects Aim: We sought to determine if testosterone replacement therapy (TRT) is associated with worse clinical outcomes Methods: Through a retrospective chart review, we identified 32 men diagnosed with COVID-19 and on TRT They were propensity score matched to 63 men diagnosed with COVID-19 and not on TRT Data regarding comorbidities and endpoints such as hospital admission, intensive care unit admission, ventilator utilization, thromboembolic events, and death were extracted Chi-square and Kruskal-Wallis tests examined differences in categorical and continuous variables, respectively Logistic regression analysis tested the relationship between TRT status and the study endpoints Results: There were no statistically significant differences between the 2 groups, and TRT was not a predictor of any of the endpoints on multivariate analysis Conclusion: These results suggest that TRT is not associated with a worse clinical outcome in men diagnosed with COVID-19 Copyright (C) 2020, International Society for Sexual Medicine Published by Elsevier Inc All rights reserved

is ?:annotates of