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?:abstract
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Objective: CT is important in the care of patients with COVID-19 pneumonia However, specificity might be poor in the absence of a clinical and epidemiological context The goal of this work was to systematically evaluate two novel CT features (sharp margin and geographic shape) of COVID-19 pneumonia Methods: All patients with reverse transcription polymerase chain reaction proven COVID-19 pneumonia and chest CT between March first and April 15, 2020 were retrospectively identified from two tertiary care hospitals in Germany The CTs were evaluated regarding the presence of typical CT signs (e g ground glass opacitiy, consolidation, crazy paving) Moreover, the shape of the opacifications (round, geographic, curvilinear) and their margin (unsharp, sharp) was determined Results: The study population comprised 108 patients (64 male) with a mean age of 59 6 years Ground glass opacities (96%) and consolidation (75%) were the most prevalent CT signs Crazy paving was seen in 17%, bronchial dilatation in 21%, air bronchogram in 29%, vessel enlargement in 47%, cavitation in 0%, lymphadenopathy in 32%, pleural effusion in 16% Round configuration of densities was present in 41% of CTs, geographic shape in 27% and curvilinear opacities in 44% 79% of opacifications were at least partially sharply marginated In almost all cases, the lung was affected bilaterally (94%) Conclusion: The CT pattern of COVID-19 pneumonia in a cohort from Germany was in accordance with prior studies However, we identified two novel CT signs of COVID-19 pneumonia which have so far not been systematically evaluated A sharp border and geographic shape of opacifications were frequently observed Advances in knowledge: The newly described CT features \'sharp margin\' and \'geographic shape\' of opacifications in patients with COVID-19 pneumonia might help to increase specificity of CT
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