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?:abstract
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To determine the effect renin-angiotensin system blockers on the outcome in patients with hypertension and concurrent COVID-19 infection, we searched PubMed, the Cochrane Library, and Google Scholar for relevant articles. Twelve studies with a total of 16,101 patients met the inclusion criteria. The mortality rate among the users of angiotensin converting enzyme inhibitors or angiotensin receptor blockers was 12.15% and in non-users it was 14.56% (risk ratio 0.70, 95% CI [0.53-0.91], P < 0.007). There was no difference in the risk of death between the use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers (risk ratio 1.09, 95% CI [0.90 -1.32]). We conclude that the use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers improves mortality in patients with hypertension and concurrent COVID-19 infection, without a significant difference between ACEIs and ARBs in this population.
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?:doi
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?:doi
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?:journal
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J_Cardiovasc_Pharmacol_Ther
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?:license
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?:pdf_json_files
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document_parses/pdf_json/06e93fd31bd5f8f6f8c247abbe996d73d60bcc24.json
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document_parses/pmc_json/PMC7404086.xml.json
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?:pmid
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?:pmid
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?:publication_isRelatedTo_Disease
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?:sha_id
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?:source
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?:title
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Renin-Angiotensin System Blockade and Mortality in Patients With Hypertension and COVID-19 Infection
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?:type
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?:year
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