PropertyValue
?:abstract
  • The world is currently facing the COVID-19 pandemic caused by the SARS-CoV-2 virus The pandemic is causing the death of people around the world, and public and social health measures to slow or prevent the spread of COVID-19 are being implemented with the involvement of all members of society Research institutions are accelerating the discovery of vaccines and therapies for COVID-19 In this work, molecular docking was used to study (in silico) the interaction of 24 ligands, divided into four groups, with four SARS-CoV-2 receptors, Nsp9 replicase, main protease (Mpro), NSP15 endoribonuclease, and spike protein (S-protein) interacting with human ACE2 The results showed that the antimalarial drug Metaquine and anti-HIV antiretroviral Saquinavir interacted with all the studied receptors, indicating that they are potential candidates for multitarget drugs for COVID-19
is ?:annotates of
?:creator
?:journal
  • Journal_of_Proteome_Research
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Interaction of drug candidates with various SARS-CoV-2 receptors: an in silico study to combat COVID-19. (Special Issue: Proteomics and its application in pandemic diseases.)
?:type
?:who_covidence_id
  • #960271
?:year
  • 2020

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