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A 40-year-old female was found to have strongly neutralising SARS-CoV-2 breastmilk IgA and IgG antibodies reactive against multiple SARS-CoV-2 antigens at 2.5 months after documented infection with SARS-CoV-2. At 6.5 months following infection she remained positive for breastmilk and serum SARS-CoV-2 neutralising antibodies. Holder breast milk pasteurisation did not diminish SARS-CoV-2 antibody titres but it reduced its neutralising capacity, while serum heat inactivation had no negative effect on SARS-CoV-2 serum antibody levels and neutralising capacity. Current data on SARS-CoV-2 and breastmilk is reviewed.
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Detection of breastmilk antibodies targeting SARS-CoV-2 nucleocapsid, spike and receptor-binding-domain antigens
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