PropertyValue
?:abstract
  • We performed a retrospective study of Covid-19 in people with HIV (PWH). PWH with Covid-19 demonstrated severe lymphopenia and decreased CD4+ T cell counts. Levels of inflammatory markers, including C-reactive protein, fibrinogen, D-dimer, interleukin-6, interleukin-8, and TNF-alpha were commonly elevated. In all, 19/72 hospitalized individuals (26.4%) died and 53 (73.6%) recovered. PWH who died had higher levels of inflammatory markers and more severe lymphopenia than those who recovered. These findings suggest that PWH remain at risk for severe manifestations of Covid-19 despite ART and that those with increased markers of inflammation and immune dysregulation are at risk for worse outcomes.
?:creator
?:doi
  • 10.1093/infdis/jiaa380
?:doi
?:journal
  • J_Infect_Dis
?:license
  • no-cc
?:pdf_json_files
  • document_parses/pdf_json/ebb38d3df2f22ebae50faa01d7d9c9ab95e6bd3f.json
?:pmcid
?:pmid
?:pmid
  • 32601704.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Clinical outcomes and immunologic characteristics of Covid-19 in people with HIV
?:type
?:year
  • 2020-06-30

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