| Property | Value |
|---|
|
?:abstract
|
-
RATIONALE: Oxygen saturation to fraction of inspired oxygen ratio (SpO(2)/FiO(2)) has been described as potential predictor of poor outcome for COVID-19, without considering its time-varying behavior though. METHODS: Prognostic value of SpO(2)/FiO(2) was evaluated by jointly modeling the longitudinal responses of SpO(2)/FiO(2) and time-to-event data retrieved from 280 severe and critically ill (intensive care) patients with COVID-19. RESULTS: A sharply decrease of SpO(2)/FiO(2) from the first to second measurement for non-survivors was observed, and a strong association between square root SpO(2)/FiO(2) and mortality risk was demonstrated, with a unit decrease in the marker corresponding to 1.82-fold increase in mortality risk (95% CI: 1.56–2.13). CONCLUSIONS: The current study suggested that SpO(2)/FiO(2) could serve as a non-invasive prognostic marker to facilitate early adjustment for treatment, thus improving overall survival.
|
|
?:creator
|
|
|
?:doi
|
-
10.1186/s12931-020-01455-4
|
|
?:doi
|
|
|
?:journal
|
|
|
?:license
|
|
|
?:pdf_json_files
|
-
document_parses/pdf_json/377a8977384cfa3d8e775e8067e377b6bb4ea36c.json
|
|
?:pmc_json_files
|
-
document_parses/pmc_json/PMC7374662.xml.json
|
|
?:pmcid
|
|
|
?:pmid
|
|
|
?:pmid
|
|
|
?:publication_isRelatedTo_Disease
|
|
|
?:sha_id
|
|
|
?:source
|
|
|
?:title
|
-
Continuously available ratio of SpO(2)/FiO(2) serves as a noninvasive prognostic marker for intensive care patients with COVID-19
|
|
?:type
|
|
|
?:year
|
|
![[This page as RDF]](https://research.tib.eu/covid-19/static/rdf-icon.gif){kind=icon}