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Reports of the incidence of acute kidney injury (AKI) in patients with COVID-19 have varied greatly from 0.5% to as high as 39%, with onset generally within 7 days from time of admission(1). The nature of the kidney insult is acute tubular necrosis, immune cell infiltration or rhabdomyolysis as demonstrated in autopsy reports(2)(,)(3). Moreover, infection with COVID-19 has been associated with coagulation abnormalities(4), as well as complement-mediated generalized thrombotic microvascular injury(5). These patients have been found to have high D-dimer, fibrin degradation product and fibrinogen values, an elevated INR, normal PTT and normal platelet counts. Renal artery thrombosis is a rare condition, the most common cause of which is atrial fibrillation. However, bilateral completely occlusive renal artery thrombosis is even rarer. We present a case of a patient with COVID-19 on systemic anticoagulation who presented with a serum creatinine of 6.04mg/dL requiring the initiation of kidney replacement therapy and was found to have bilateral renal artery thrombosis.
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10.1016/j.xkme.2020.07.010
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document_parses/pdf_json/a2c2225c11334a4dd5752077deee986632544b6e.json
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document_parses/pmc_json/PMC7654329.xml.json
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Bilateral Renal Artery Thrombosis in a Patient With COVID-19
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