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First-line treatment for children under the age of 6 years is PBMT Tips for prescribing stimulant medications IIn mostcases,the long-acting form of the medication is desirable 9 L Start with the lowest dose 3 Titrate weekly to the most effective dose with acceptable side effects1 4 Follow up by phone or electronic messages, or virtual visits with weekly titration, utilizing trained office staff and/or templates for obtaining information 5 Follow up visit within 30 days including height, weight, pulse, blood pressure, physical exam6 6 Use rating scales to measure improvement in ADHD symptoms and impairment 7 If intolerable side effects on first class of stimulants initiated, switch to the other class of stimulant medication Primary care visits are recommended every 6 months for children receiving treatment for ADHD, more frequently with medication changes, intolerable medication side effects, appearance of new or worsening symptoms, or concern fornew co-occurring mental health disorders 1 Other treatment modalities Newly emerging treatment modalities for ADHD include trigeminal nerve stimulation (TNS) and digital therapeutics Trigeminal nerve stimulation for treatment of ADHD was evaluated in a double-blind, sham-controlled study supported by the National Institutes of Mental Health and showed few side effects and modest effect size in children 7 The TNS device gained FDA approval for treatment of ADHD in children aged 7-12 years that are not on medication 8 A new game-based digital therapeutic was given FDA approval following a randomized controlled trial that showed minimal side effects and some improvement with inattention in children aged 8-12 years that were not on medication 9\'10 Although they have low risk of side effects in early studies and have gained FDA approval, these new modalities do not have studies proving adequate effectiveness to replace existing treatments
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