PropertyValue
?:abstract
  • A novel coronavirus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a current outbreak of infection termed Coronavirus Disease 2019 (COVID-19) by the World Health Organization (WHO). COVID-19 is currently a global pandemic that may cause close to half a billion deaths around the world. Until now, there is no effective treatment for COVID-19. Quinacrine (Qx) has been used since the 1930s as preventive antimalarial compound. It is a recognized small molecule inhibitor of RNA virus replication, with known anti-prion activity, and identified as a potent Ebola virus inhibitor both in vitro and in vivo. Recently, Qx has showed anti-SARS-CoV-2 activity. Herein, we review the potential mechanisms associated with quinacrine as an antiviral compound.
?:creator
?:doi
?:doi
  • 10.26355/eurrev_202101_24428
?:journal
  • European_review_for_medical_and_pharmacological_sciences
?:license
  • unk
?:pmid
?:pmid
  • 33506949
?:publication_isRelatedTo_Disease
?:source
  • Medline
?:title
  • Quinacrine as a potential treatment for COVID-19 virus infection.
?:type
?:year
  • 2021-01-01

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